Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 19.09
Human Site: S566 Identified Species: 26.25
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S566 V N S L G V S S L E H I T H S
Chimpanzee Pan troglodytes XP_519198 1283 142803 S566 V N S L G V S S L E H I T H S
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S564 V N S L G V S S L E H I T H S
Dog Lupus familis XP_532459 1267 140567 S550 V N S L G V S S L E H I T H S
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 A567 V S A L G A S A M E H I T H S
Rat Rattus norvegicus P46462 806 89330 Y173 V E T D P S P Y C I V A P D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 D531 S S L G G V S D L G A T L L D
Chicken Gallus gallus XP_418655 1290 143066 S574 V D K L G T S S F E H I S H S
Frog Xenopus laevis P23787 805 89193 P172 V V E T D P S P Y C I V A P D
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 Y173 V E T D P S P Y C I V A P D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 E168 K V V L T D P E P Y C I V A P
Honey Bee Apis mellifera XP_397107 1069 120490 L436 A V I D E A A L R D T K V R V
Nematode Worm Caenorhab. elegans P54812 810 89622 P177 V V E T D P A P A C I V A P D
Sea Urchin Strong. purpuratus XP_797089 1508 166130 A720 M A T L G S G A L E H I T A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322 A182 P A E Y C V V A P D T E I F C
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 H410 V K D I I E R H L P K H Y H V
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 V616 E D S A I D E V L G L I A A T
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 100 100 100 N.A. 66.6 6.6 N.A. 26.6 66.6 13.3 6.6 N.A. 13.3 0 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. 33.3 80 20 20 N.A. 13.3 13.3 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 6.6 20 20
P-Site Similarity: N.A. N.A. N.A. 20 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 12 6 6 0 12 12 18 6 0 6 12 18 18 0 % A
% Cys: 0 0 0 0 6 0 0 0 12 12 6 0 0 0 6 % C
% Asp: 0 12 6 18 12 12 0 6 0 12 0 0 0 12 18 % D
% Glu: 6 12 18 0 6 6 6 6 0 42 0 6 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 6 0 0 0 0 6 0 % F
% Gly: 0 0 0 6 48 0 6 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 42 6 0 42 0 % H
% Ile: 0 0 6 6 12 0 0 0 0 12 12 53 6 0 0 % I
% Lys: 6 6 6 0 0 0 0 0 0 0 6 6 0 0 0 % K
% Leu: 0 0 6 48 0 0 0 6 48 0 6 0 6 6 0 % L
% Met: 6 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 6 0 0 0 12 12 18 12 12 6 0 0 12 12 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 6 0 6 0 0 0 0 6 0 % R
% Ser: 6 12 30 0 0 18 48 30 0 0 0 0 6 0 36 % S
% Thr: 0 0 18 12 6 6 0 0 0 0 12 6 36 0 24 % T
% Val: 65 24 6 0 0 36 6 6 0 0 12 12 12 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 12 6 6 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _